HMX-12 Multi (ToHeart) will always be by 2D best friend (not wife). She'll never be replaced by any other bishoujo. Although I do like some other characters a lot as well , she'll always be #1.
My favorite male character is Madarame Harunobu (Genshiken). I never really like many male characters, but he's the one rare guy I like a lot. The other guys in Genshiken are good too, but Madarame is the best.
Oh god i was friggen surprised she was taken as a waifu because i never thought "Freezing" would be known with only 30 chapters translated to this date ._. . (Never underestimate FAKKU's wide community >_>)
She's just so so so sweet(and hawt but that goes without saying):