One piece was the first anime to ever make me cry. Sword Art online was the second anime to make me cry and... I think Eden of the east but those were tears of joy.
Well only one has made me cry and I know this was over a decade ago and is pretty out of the ordinary but I actually cried on a certain scene of the first pokemon movie in a movie theater. Aw man, the scene where ash turned to stone and pikachu kept trying to revive him with electricity while crying and screaming out "pika-pi".......heh, just remembering that scene makes me both sad and embarrassed at the same time because at that time a tear slowly descended down my cheek without me even realizing it. I guess I was a lightweight way back then because I haven't cried to anything media related since then.