For me personally I wouldn't sit still in just a single martial arts. I'd probably perfect my Karate but the few martial arts I'd really like to master would be Wing Chun, Kung Fu, Muay Thai and Taichi. :)
If I could master a martial art, it would be the "Invincible Martial Arts Style" or something, that way, I am a master of an unbeatable art, and would be able to defeat any attackers, even other martial arts masters, with relative ease.
Probably capoeira or muay thai when it comes to unarmed combat.
I did some taekwondo when i was younger but i did not like it that much.
(And i got kicked in the back.. Helloo~~ back problems)
When it comes to armed combat i'd love to learn a spear or staff style of some sort :)
If I could master ANY martial art, I'd master ALL of them. After all, "All martial arts under the heavens" is a valid 'martial art', but none have ever 'mastered' it.