of course I'd want this, current mouse pad is getting worn out, thou I doubt this will get manufactured and mass produced quick enough, by I do see it happening just not yet
Being an oppai mousepad collector, I would say the strippable speaking oppai mousepad is quite an original idea. The current oppai mousepads are already selling well enough and these added features may attract further customers.
To top it off, the production team should hire a well-known female seiyuu to voice the mousepad. *Insert favourite seiyuu name here*. :D