Thanks. I should really subscribe to Vaati one day, or I'll keep missing this stuff.
"They are replacing magic with gadgets, guns and such. Main mechanic seems to be related to blood and blood is also used to regain your HP and gain various other benefits."
"You get blood sucking it from corpses or items. Sucking too much blood will turn you into a beast which I suppose is this game’s Soul/Hollow form. The game will apparently become a lot harder to play/control when in beast mode. To become a human again you need human blood and is where the online component comes into play," reads the details from Famitsu as translated by NeoGaf user.
Blood mechanic sounds amazing because in the Souls series you would consume souls but besides moral implications there wasn't really much weight to doing so. I also love the idea of offensive gameplay in Bloodborne, there were too many encounters in the souls series that were passive and favored shield builds.
On a side note the weapon that the Bloodborne is using in the clips is a double barreled shotgun, so expecting lever-action guns is not too far fetched?